《中国神经再生研究（英文版）》杂志最新发布

NEURAL REGENERATION RESEARCH

Vol 18｜No. 2｜February 2023

www.nrronline.org

综述

Functions and mechanisms of cytosolic phospholipase A2 in central nervous system trauma

胞浆型磷脂酶A2在中枢神经系统创伤中的功能和机制

Hao-Jie Zhang, Yi-Tuo Chen, Xin-Li Hu, Wan-Ta Cai, Xiang-Yang Wang, Wen-Fei Ni, Kai-Liang Zhou

The mechanism and relevant mediators associated with neuronal apoptosis and potential therapeutic targets in subarachnoid hemorrhage

蛛网膜下腔出血后神经细胞凋亡的机制、介质及潜在的治疗靶点

Qi Tian, Sheng Liu, Shou-Meng Han, Wei Zhang, Xian-Yao Qin, Jun-Hui Chen, Cheng-Li Liu, Yu-Jia Guo, Ming-Chang Li

Simulating traumatic brain injury in vitro: developing high throughput models to test biomaterial based therapies

体外模拟创伤性脑损伤：开发高通量模型以测试基于生物材料的疗法

Raja Haseeb Basit, Jessica Wiseman, Farhana Chowdhury, Divya Maitreyi Chari

Brain and spinal cord trauma: what we know about the therapeutic potential of insulin growth factor 1 gene therapy

脑和脊髓创伤：我们对胰岛素生长因子 1 基因治疗的治疗潜力的了解

María Jose Bellini, Florencia Labombarda

The potential of gene therapies for spinal cord injury repair: a systematic review and meta-analysis of pre-clinical studies

脊髓损伤修复中基因疗法的潜力：临床前研究的系统评价和荟萃分析

Catriona J. Cunningham, Mindaugas Viskontas, Krzysztof Janowicz, Yasmin Sani, Malin E. Håkansson, Anastasia Heidari, Wenlong Huang, Xuenong Bo

Microglia depletion as a therapeutic strategy: friend or foe in multiple sclerosis models?

小胶质细胞耗竭作为一种治疗策略：多发性硬化模型中的朋友还是敌人？

Victoria Sofia Berenice Wies Mancini, Anabella Ayelen Di Pietro, Laura Andrea Pasquini

Safety, immunogenicity, efficacy, and acceptability of COVID-19 vaccination in people with multiple sclerosis: a narrative review

COVID-19 疫苗在多发性硬化患者中的安全性、免疫原性、有效性和可接受性：叙述性文献综述

Fioravante Capone, Mariagrazia Rossi, Alessandro Cruciani, Francesco Motolese, Fabio Pilato, Vincenzo Di Lazzaro

c-Abl kinase at the crossroads of healthy synaptic remodeling and synaptic dysfunction in neurodegenerative diseases

c-Abl 激酶处于神经退行性疾病中健康突触重塑和突触功能障碍的十字路口

Daniela A. Gutiérrez, América Chandía-Cristi, María José Yáñez, Silvana Zanlungo, Alejandra R. Álvarez

Mortalin/Hspa9 involvement and therapeutic perspective in Parkinson’s disease

Mortalin/Hspa9 在帕金森病中的参与和治疗前景

Baptiste Texier, Morgane Prime, Djamaa Atamena, Pascale Belenguer, Marion Szelechowski

Cre-recombinase systems for induction of neuron-specific knockout models: a guide for biomedical researchers

用于诱导神经元特异性敲除模型的 Cre 重组酶系统：生物医学研究人员的向导

Tetiana Shcholok, Eftekhar Eftekharpour

Prenatal programing of motivated behaviors: can innate immunity prime behavior?

动机行为的产前编程：先天免疫能引发行为吗？

Larisa Montalvo-Martínez, Gabriela Cruz-Carrillo, Roger Maldonado-Ruiz, Luis A. Trujillo-Villarreal, Eduardo A. Garza-Villarreal, Alberto Camacho-Morale

观点

Approaches to quantify axonal morphology for the analysis of axonal degeneration

量化轴突形态以分析轴突变性的方法

Alex Palumbo, Marietta Zille

Advances in quantitative analysis of astrocytes using machine learning

利用机器学习对星形胶质细胞进行定量分析的进展

Demetrio Labate, Cihan Kayasandik

The role of mitochondria in the recovery of neurons after injury

线粒体在损伤后的神经元恢复中的作用

Taylor McElroy, Rola S. Zeidan, Laxmi Rathor, Sung Min Han, Rui Xiao

Kainate receptors in the CA2 region of the hippocampus

海马 CA2 区的红藻氨酸受体

Yuniesky Andrade-Talavera, Antonio Rodríguez-Moreno

(Phospho)creatine: the reserve and merry-go-round of brain energetics

(磷酸）肌酸：大脑能量的储备和快乐的轮回

Hong-Ru Chen, Ton DeGrauw, Chia-Yi Kuan

Understanding the timing of brain injury in fetal growth restriction: lessons from a model of spontaneous growth restriction in piglets

了解胎儿生长受限导致脑损伤的时机：来自仔猪自发生长受限模型的经验教训

Hannah Musco, Julie A. Wixey

MicroRNA-based targeting of the Rho/ROCK pathway in therapeutic strategies after spinal cord injury

脊髓损伤后治疗策略中基于 MicroRNA 的 Rho/ROCK 通路靶向

Tetsu Kimura, Yuta Horikoshi

A perspective on causality assessment in epigenetic research on neurodegenerative disorders

神经退行性疾病表观遗传学研究中因果关系评估的观点

Philippos Koulousakis, Assia Tiane, Niels Hellings, Jos Prickaerts, Daniel van den Hove, Tim Vanmierlo

Synaptopathy in CHMP2B frontotemporal dementia highlights the synaptic vesicle cycle as a therapeutic target

CHMP2B 额颞叶痴呆的突触病变突出突触小泡周期作为治疗靶点

Miranda Robbins, Emma L. Clayton

Microtubule affinity regulating kinase (MARK/Par1) isoforms differentially regulate Alzheimer’s disease-like TAU missorting and Aβ-mediated mediated synapse pathology

微管亲和调节激酶 (MARK/Par1) 亚型差异调节阿尔茨海默病样 TAU 错配和 Aβ 介导的突触病理学

Jana Chudobová, Hans Zempel

Turning up the NAD+-mitophagy axis to treat Alzheimer’s disease

调高 NAD+-mitophagy 轴以治疗阿尔茨海默病

Evandro F. Fang, Alexander Anisimov

Acid-sensing ion channel 1a: a novel target in Alzheimer’s disease?

酸感应离子通道 1a：阿尔茨海默病的新靶点？

Dalila Mango, Robert Nisticò

The Wnt/β-catenin signaling: a multifunctional target for neuroprotective and regenerative strategies in Parkinson’s disease

Wnt/β-连环蛋白信号：帕金森病神经保护和再生策略的多功能靶点

Annalucia Serafino, Mauro Cozzolino

Apoptotic retinal ganglion cell loss is accompanied by complement and cytokine response in the βB1-CTGF primary open-angle glaucoma mouse model

在βB1-CTGF原发性开角型青光眼小鼠模型中，凋亡性视网膜神经节细胞丢失伴随着补体和细胞因子反应

Ana Maria Mueller-Buehl, Sabrina Reinehr

Schwann cell extracellular vesicles: judging a book by its cover

许旺细胞胞外囊泡：从封面判断一本书

Steven L. Gonias, Wendy M. Campana

Perspective on inflammatory cytokines in open spinal dysraphism

开放性脊柱裂中炎性细胞因子的观点

Friederike Knerlich-Lukoschus

On the interaction of a donepezil huprine hybrid with synthetic membrane models

多奈哌齐石杉碱杂种与合成膜模型的相互作用

Pablo Zambrano

评论

Commentary on “PANoptosis-like cell death kills retinal neurons following OGD/R and aHIOP injury”

关于PANoptosis样细胞死亡杀死OGD/R和AHIOP损伤后的视网膜神经元的评论文章

Macarena S. Arrázola, Felipe A. Court

Potential role of PANoptosis in neuronal cell death: comment on ‘PANoptosis-like cell death kills retinal neurons following OGD/R and aHIOP injury’

PANoptosis 在神经元细胞死亡中的潜在作用：评论“PANoptosis 样细胞死亡在 OGD/R 和 aHIOP 损伤后杀死视网膜神经元”

Yanyan Sun, Changlian Zhu

PANoptosis: new insights in regulated cell death in ischemia/reperfusion models

PANoptosis：缺血/再灌注模型中调节细胞死亡的新见解

Paloma González-Rodríguez, Arsenio Fernández-López

研究原著

脑损伤与神经再生

Neural stem cell-derived exosome as a nano-sized carrier for BDNF delivery to a rat model of ischemic stroke

神经干细胞源性外泌体作为纳米级载体向缺血性脑卒中模型递送脑源性神经营养因子

Zhi-Han Zhu, Feng Jia, Waqas Ahmed, Gui-Long Zhang, Hong Wang, Chao-Qun Lin, Wang-Hao Chen, Lu-Kui Chen

Modified constraint-induced movement therapy enhances cortical plasticity in a rat model of traumatic brain injury: a resting-state functional MRI study

改良的约束诱导运动疗法干预可脑创伤大鼠的大脑皮质可塑性

Cheng-Cheng Sun, Yu-Wen Zhang, Xiang-Xin Xing, Qi Yang, Ling-Yun Cao, Yu-Feng Cheng, Jing-Wang Zhao, Shao-Ting Zhou, Dan-Dan Cheng, Ye Zhang, Xu-Yun Hua, He Wang, Dong-Sheng Xu

Knockout of Sirt2 alleviates traumatic brain injury in mice

敲除沉默信息调节因子2基因可减轻创伤性脑损伤

Wei Wang, Qiu-Yuan Gong, Lin Cai, Yao Jing, Dian-Xu Yang, Fang Yuan, Hao Chen, Heng-Li Tian

Repetitive transcranial magnetic stimulation promotes neurological functional recovery in rats with traumatic brain injury by upregulating synaptic plasticity-related proteins

重复经颅磁刺激上调突触可塑性相关蛋白促进创伤性脑损伤后的神经功能恢复

Fang-Fang Qian, You-Hua He, Xiao-Hui Du, Hua-Xiang Lu, Ren-Hong He, Jian-Zhong Fan

Treatment of radiation-induced brain injury with bisdemethoxycurcumin

双去甲氧基姜黄素可治疗辐射性脑损伤

Yun-Qian Chang, Gui-Juan Zhou, Hong-Mei Wen, Duan-Qun He, Chen-Lin Xu, Ya-Rui Chen, Yi-Hui Li, Shuang-Xi Chen, Zi-Jian Xiao, Ming Xie

A novel aged mouse model of recurrent intracerebral hemorrhage in the bilateral striatum

一种新型双侧纹状体复发性脑出血的老年小鼠模型

Li-Min Wang, Zhi-Hua Liu, Hong-Lei Ren, Xue-Mei Chen, Jun-Min Wang, Hui-Min Cai, Li-Ping Wei, Hui-Hong Tian, Jian Wang, Li-Juan Wang

β-Estradiol 17-acetate enhances the in vitro vitality of endothelial cells isolated from the brain of patients subjected to neurosurgery

β-雌二醇17-乙酸酯可提高神经外科患者大脑内皮细胞的活力

Sonia Guzzo, Pasquale De Bonis, Barbara Pavan, Luciano Fadiga

脊髓损伤与神经再生

Knockdown of polypyrimidine tract binding protein facilitates motor function recovery after spinal cord injury

敲低多嘧啶束结合蛋白可促进脊髓损伤后运动功能的恢复

Ri-Yun Yang, Rui Chai, Jing-Ying Pan, Jing-Yin Bao, Pan-Hui Xia, Yan-Kai Wang, Ying Chen, Yi Li, Jian Wu, Gang Chen

Nicotinic acetylcholine signaling is required for motor learning but not for rehabilitation from spinal cord injury

烟碱乙酰胆碱有助于脊髓损伤后运动恢复但非康复训练促进运动功能恢复所必需

Yue Li, Edmund R. Hollis II

Identification of injury type using somatosensory and motor evoked potentials in a rat spinal cord injury model

体感和运动诱发电位联合监测识别手术致机械性原发性脊髓损伤的类型

Rong Li, Han-Lei Li, Hong-Yan Cui, Yong-Can Huang, Yong Hu

Effects of C2 hemisection on respiratory and cardiovascular functions in rats

C2脊髓半切对大鼠呼吸和心血管功能的影响

Pauline Michel-Flutot, Arnaud Mansart, Abdallah Fayssoil, Stéphane Vinit

神经退行性疾病与神经再生

The Alzheimer’s disease-associated gene TREML2 modulates inflammation by regulating microglia polarization and NLRP3 inflammasome activation

阿尔茨海默病治疗的新标靶：TREML2通过调节小胶质细胞极化和 NLRP3 炎性体激活来调节炎症

Si-Yu Wang, Xin-Xin Fu, Rui Duan, Bin Wei, Hai-Ming Cao, Yan E, Shuai-Yu Chen, Ying-Dong Zhang, Teng Jiang

周围神经损伤与神经再生

Functional recovery and muscle atrophy in pre-clinical models of peripheral nerve transection and gap-grafting in mice: effects of 4-aminopyridine

周围神经横断和缺损移植的临床前小鼠模型的功能恢复和肌肉萎缩：4-氨基吡啶的作用

Jung Il Lee, M A Hassan Talukder, Zara Karuman, Anagha A. Gurjar, Prem Kumar Govindappa, Jagadeeshaprasad M. Guddadarangaiah, Kristen M. Manto, Grant D. Wandling, John P. Hegarty, David L. Waning, John C. Elfar

Platelet-rich plasma promotes peripheral nerve regeneration after sciatic nerve injury

富血小板血浆可有效促进损伤坐骨神经后周围神经的再生

Su-Long Wang, Xi-Lin Liu, Zhi-Chen Kang, Yue-Shu Wang

视神经损伤与神经再生

PANoptosis-like cell death in ischemia/reperfusion injury of retinal neurons

缺血再灌注损伤视网膜神经元泛死亡样细胞死亡

Wei-Tao Yan, Wen-Juan Zhao, Xi-Min Hu, Xiao-Xia Ban, Wen-Ya Ning, Hao Wan, Qi Zhang, Kun Xiong

Neuroprotective effects of exogenous brain-derived neurotrophic factor on amyloid-beta 1–40-induced retinal degeneration

外源性脑源性神经营养因子对淀粉样β蛋白1-40致视网膜变性的神经保护

Mohd Aizuddin Mohd Lazaldin, Igor Iezhitsa, Renu Agarwal, Puneet Agarwal, Nafeeza Mohd Ismail

Sox11b regulates the migration and fate determination of Müller glia-derived progenitors during retina regeneration in zebrafish

Sox11b可调节斑马鱼视网膜再生过程中 Müller 胶质祖细胞的迁移和命运

Kaida Song, Zihao Lin, Lining Cao, Bowen Lu, Yuxi Chen, Shuqiang Zhang, Jianfeng Lu, Hui Xu

Anti-inflammatory effect of miR-125a-5p on experimental optic neuritis by promoting the differentiation of Treg cells

miR-125a-5p促进调节性T细胞分化对视神经炎的抗炎效应

Jia-Lin Zhan, Yan-Ling Huang, Qiao-Wen Liang, Xiao-Sheng Qu, Zi-Mei Dong, Yi Du, Wen-Jing Luo

疼痛与神经再生

Intrathecal liproxstatin-1 delivery inhibits ferroptosis and attenuates mechanical and thermal hypersensitivities in rats with complete Freund’s adjuvant-induced inflammatory pain

鞘内注射利普司他汀1抑制铁死亡并减轻炎性疼痛

Yi-Fan Deng, Ping Xiang, Jing-Yi Du, Jian-Fen Liang, Xiang Li

读者来信

Emerging evidence of neuronal cellstargeting SARS-CoV-2 causing anosmia associated with COVID-19

靶向神经元细胞的SARS-CoV-2引起COVID-19相关失嗅症的新证据

Abdul Mannan Baig